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ROR activation by Nobiletin enhances antitumor efficacy via suppression of IκB/NF-κB signaling in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is a heterogeneous disease characterized by poor response to standard therapies and therefore unfavorable clinical outcomes. Better understanding of TNBC and new therapeutic strategies are urgently needed. ROR nuclear receptors are multifunctional transcription f...

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Detalles Bibliográficos
Autores principales: Kim, Eunju, Kim, Yoon-Jin, Ji, Zhiwei, Kang, Jin Muk, Wirianto, Marvin, Paudel, Keshav Raj, Smith, Joshua A., Ono, Kaori, Kim, Jin-Ah, Eckel-Mahan, Kristin, Zhou, Xiaobo, Lee, Hyun Kyoung, Yoo, Ji Young, Yoo, Seung-Hee, Chen, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018867/
https://www.ncbi.nlm.nih.gov/pubmed/35440077
http://dx.doi.org/10.1038/s41419-022-04826-5