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Effect of mGluR2 Positive Allosteric Modulation on Frontostriatal Working Memory Activation in Schizophrenia

Negative symptoms and cognitive deficits contribute strongly to disability in schizophrenia, and are resistant to existing medications. Recent drug development has targeted enhanced NMDA function by increasing mGluR2/3 signaling. However, the clinical utility of such agents remains uncertain, and ma...

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Detalles Bibliográficos
Autores principales:	Wolf, Daniel H., Zheng, David, Kohler, Christian, Turetsky, Bruce I., Ruparel, Kosha, Satterthwaite, Theodore D., Elliott, Mark A., March, Mary E., Cross, Alan J., Smith, Mark A., Zukin, Stephen R., Gur, Ruben C., Gur, Raquel E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018886/ https://www.ncbi.nlm.nih.gov/pubmed/34667261 http://dx.doi.org/10.1038/s41380-021-01320-w

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