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Normalizing and denoising protein expression data from droplet-based single cell profiling

Multimodal single-cell profiling methods that measure protein expression with oligo-conjugated antibodies hold promise for comprehensive dissection of cellular heterogeneity, yet the resulting protein counts have substantial technical noise that can mask biological variations. Here we integrate expe...

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Detalles Bibliográficos
Autores principales: Mulè, Matthew P., Martins, Andrew J., Tsang, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018908/
https://www.ncbi.nlm.nih.gov/pubmed/35440536
http://dx.doi.org/10.1038/s41467-022-29356-8