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Normalizing and denoising protein expression data from droplet-based single cell profiling
Multimodal single-cell profiling methods that measure protein expression with oligo-conjugated antibodies hold promise for comprehensive dissection of cellular heterogeneity, yet the resulting protein counts have substantial technical noise that can mask biological variations. Here we integrate expe...
Autores principales: | Mulè, Matthew P., Martins, Andrew J., Tsang, John S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018908/ https://www.ncbi.nlm.nih.gov/pubmed/35440536 http://dx.doi.org/10.1038/s41467-022-29356-8 |
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