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An anti-influenza A virus microbial metabolite acts by degrading viral endonuclease PA

The emergence of new highly pathogenic and drug-resistant influenza strains urges the development of novel therapeutics for influenza A virus (IAV). Here, we report the discovery of an anti-IAV microbial metabolite called APL-16-5 that was originally isolated from the plant endophytic fungus Aspergi...

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Detalles Bibliográficos
Autores principales:	Zhao, Jianyuan, Wang, Jing, Pang, Xu, Liu, Zhenlong, Li, Quanjie, Yi, Dongrong, Zhang, Yongxin, Fang, Xiaomei, Zhang, Tao, Zhou, Rui, Guo, Zhe, Liu, Wancang, Li, Xiaoyu, Liang, Chen, Deng, Tao, Guo, Fei, Yu, Liyan, Cen, Shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019042/ https://www.ncbi.nlm.nih.gov/pubmed/35440123 http://dx.doi.org/10.1038/s41467-022-29690-x

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