Inhibition of Macrophage Migration Inhibitory Factor Activity Attenuates Haemorrhagic Shock-Induced Multiple Organ Dysfunction in Rats

OBJECTIVE: The aim of this study was to investigate (a) macrophage migration inhibitory factor (MIF) levels in polytrauma patients and rats after haemorrhagic shock (HS), (b) the potential of the MIF inhibitor ISO-1 to reduce multiple organ dysfunction syndrome (MODS) in acute (short-term and long-t...

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Detalles Bibliográficos
Autores principales: Patel, Nikita M., Yamada, Noriaki, Oliveira, Filipe R. M. B., Stiehler, Lara, Zechendorf, Elisabeth, Hinkelmann, Daniel, Kraemer, Sandra, Stoppe, Christian, Collino, Massimo, Collotta, Debora, Alves, Gustavo Ferreira, Ramos, Hanna Pillmann, Sordi, Regina, Marzi, Ingo, Relja, Borna, Marx, Gernot, Martin, Lukas, Thiemermann, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019168/
https://www.ncbi.nlm.nih.gov/pubmed/35464452
http://dx.doi.org/10.3389/fimmu.2022.886421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019168/
https://www.ncbi.nlm.nih.gov/pubmed/35464452
http://dx.doi.org/10.3389/fimmu.2022.886421

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