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Components of the human-specific, p53-mediated “kill switch” tumor suppression mechanism are usurped by human tumors, creating the possibility of therapeutic exploitation
We recently reported our detection of an anthropoid primate-specific, adrenal androgen-dependent, “kill switch” tumor suppression mechanism that is triggered by the inactivation of the p53 tumor suppressor. This mechanism reached its highest expression only in humans as a result of the human-specifi...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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OAE Publishing Inc.
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019199/ https://www.ncbi.nlm.nih.gov/pubmed/35582271 http://dx.doi.org/10.20517/cdr.2019.89 |