Cargando…

Differential and organ-specific functions of organic solute transporter α and β in experimental cholestasis

BACKGROUND & AIMS: Organic solute transporter (OST) subunits OSTα and OSTβ facilitate bile acid efflux from the enterocyte into the portal circulation. Patients with deficiency of OSTα or OSTβ display considerable variation in the level of bile acid malabsorption, chronic diarrhea, and signs of...

Descripción completa

Detalles Bibliográficos
Autores principales: van de Wiel, Sandra M.W., Porteiro, Begoña, Belt, Saskia C., Vogels, Esther W.M., Bolt, Isabelle, Vermeulen, Jacqueline L.M., de Waart, D. Rudi, Verheij, Joanne, Muncan, Vanesa, Oude Elferink, Ronald P.J., van de Graaf, Stan F.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019253/
https://www.ncbi.nlm.nih.gov/pubmed/35462858
http://dx.doi.org/10.1016/j.jhepr.2022.100463