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Extracellular signal-regulated kinase phosphorylation enhancement and Na(V)1.7 sodium channel upregulation in rat dorsal root ganglia neurons contribute to resiniferatoxin-induced neuropathic pain: The efficacy and mechanism of pulsed radiofrequency therapy
Pulsed radiofrequency (PRF) therapy is one of the most common treatment options for neuropathic pain, albeit the underlying mechanism has not been hitherto elucidated. In this study, we investigated the efficacy and mechanism of PRF therapy on resiniferatoxin (RTX)-induced mechanical allodynia, whic...
Autores principales: | Hidaka, Kotaro, Maruta, Toyoaki, Koshida, Tomohiro, Kurogi, Mio, Kage, Yohko, Kouroki, Satoshi, Shirasaka, Tetsuro, Takeya, Ryu, Tsuneyoshi, Isao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019323/ https://www.ncbi.nlm.nih.gov/pubmed/35418262 http://dx.doi.org/10.1177/17448069221089784 |
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