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Patients With Autism Spectrum Disorder and Co-occurring Substance Use Disorder: A Clinical Intervention Study

BACKGROUND: The prevalence of substance use disorders (SUD) in individuals with autism spectrum disorders (ASD) appears to be higher than previously described. Attention has been drawn to developing new treatment approaches for this patient population, as they appear to do less well with traditional...

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Autores principales: Walhout, Sharon JN, van Zanten, Johan, DeFuentes-Merillas, Laura, Sonneborn, Christina KME, Bosma, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019324/
https://www.ncbi.nlm.nih.gov/pubmed/35465619
http://dx.doi.org/10.1177/11782218221085599
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author Walhout, Sharon JN
van Zanten, Johan
DeFuentes-Merillas, Laura
Sonneborn, Christina KME
Bosma, Marc
author_facet Walhout, Sharon JN
van Zanten, Johan
DeFuentes-Merillas, Laura
Sonneborn, Christina KME
Bosma, Marc
author_sort Walhout, Sharon JN
collection PubMed
description BACKGROUND: The prevalence of substance use disorders (SUD) in individuals with autism spectrum disorders (ASD) appears to be higher than previously described. Attention has been drawn to developing new treatment approaches for this patient population, as they appear to do less well with traditional addiction treatment. There is very little research addressing treatment outcome. This study aims to introduce and evaluate a manualized group treatment intervention developed specifically for patients with ASD and co-occurring SUD. METHODS: We developed a group treatment based on cognitive behavioural therapy (CBT) and evaluated outcome measures at the end of treatment and 3-month follow-up. Fifty-seven patients with ASD and co-occurring SUD were included of which 30 completed the group intervention, 27 of them also participated at 3-month follow-up. RESULTS: The findings suggest that group treatment can work for patients with ASD and co-occurring SUD. Lower levels of alcohol use (t = 3.61, P = .002, d = 0.75), craving (t = 2.65, P = .013, d = 0.51), passive coping styles (t = 2.32, P = .030, d = 0.48), depression (t = 3.48, P = .002, d = 0.67), anxiety (t = 3.02, P = .006, d = 0.58), and stress (t = 2.62, P = .015, d = 0.51) symptoms were reported after completing the group intervention, with even stronger effects at 3 months follow-up. CONCLUSIONS: The present study shows promising results of a tailor-made group intervention in a heterogeneous patient population with ASD and co-occurring SUD with positive effects on both symptoms of ASD and SUD.
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spelling pubmed-90193242022-04-21 Patients With Autism Spectrum Disorder and Co-occurring Substance Use Disorder: A Clinical Intervention Study Walhout, Sharon JN van Zanten, Johan DeFuentes-Merillas, Laura Sonneborn, Christina KME Bosma, Marc Subst Abuse Original Research BACKGROUND: The prevalence of substance use disorders (SUD) in individuals with autism spectrum disorders (ASD) appears to be higher than previously described. Attention has been drawn to developing new treatment approaches for this patient population, as they appear to do less well with traditional addiction treatment. There is very little research addressing treatment outcome. This study aims to introduce and evaluate a manualized group treatment intervention developed specifically for patients with ASD and co-occurring SUD. METHODS: We developed a group treatment based on cognitive behavioural therapy (CBT) and evaluated outcome measures at the end of treatment and 3-month follow-up. Fifty-seven patients with ASD and co-occurring SUD were included of which 30 completed the group intervention, 27 of them also participated at 3-month follow-up. RESULTS: The findings suggest that group treatment can work for patients with ASD and co-occurring SUD. Lower levels of alcohol use (t = 3.61, P = .002, d = 0.75), craving (t = 2.65, P = .013, d = 0.51), passive coping styles (t = 2.32, P = .030, d = 0.48), depression (t = 3.48, P = .002, d = 0.67), anxiety (t = 3.02, P = .006, d = 0.58), and stress (t = 2.62, P = .015, d = 0.51) symptoms were reported after completing the group intervention, with even stronger effects at 3 months follow-up. CONCLUSIONS: The present study shows promising results of a tailor-made group intervention in a heterogeneous patient population with ASD and co-occurring SUD with positive effects on both symptoms of ASD and SUD. SAGE Publications 2022-04-17 /pmc/articles/PMC9019324/ /pubmed/35465619 http://dx.doi.org/10.1177/11782218221085599 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Research
Walhout, Sharon JN
van Zanten, Johan
DeFuentes-Merillas, Laura
Sonneborn, Christina KME
Bosma, Marc
Patients With Autism Spectrum Disorder and Co-occurring Substance Use Disorder: A Clinical Intervention Study
title Patients With Autism Spectrum Disorder and Co-occurring Substance Use Disorder: A Clinical Intervention Study
title_full Patients With Autism Spectrum Disorder and Co-occurring Substance Use Disorder: A Clinical Intervention Study
title_fullStr Patients With Autism Spectrum Disorder and Co-occurring Substance Use Disorder: A Clinical Intervention Study
title_full_unstemmed Patients With Autism Spectrum Disorder and Co-occurring Substance Use Disorder: A Clinical Intervention Study
title_short Patients With Autism Spectrum Disorder and Co-occurring Substance Use Disorder: A Clinical Intervention Study
title_sort patients with autism spectrum disorder and co-occurring substance use disorder: a clinical intervention study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019324/
https://www.ncbi.nlm.nih.gov/pubmed/35465619
http://dx.doi.org/10.1177/11782218221085599
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