A novel role for GalNAc-T2 dependent glycosylation in energy homeostasis

OBJECTIVE: GALNT2, encoding polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2), was initially discovered as a regulator of high-density lipoprotein metabolism. GalNAc-T2 is known to exert these effects through post-translational modification, i.e., O-linked glycosylation of secreted protein...

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Detalles Bibliográficos
Autores principales: Verzijl, Cristy R.C., Oldoni, Federico, Loaiza, Natalia, Wolters, Justina C., Rimbert, Antoine, Tian, E., Yang, Weiming, Struik, Dicky, Smit, Marieke, Kloosterhuis, Niels J., Fernandez, Amy J., Samara, Nadine L., Ten Hagen, Kelly G., Dalal, Kruti, Chernish, Aliona, McCluggage, Peggy, Tabak, Lawrence A., Jonker, Johan W., Kuivenhoven, Jan Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019398/
https://www.ncbi.nlm.nih.gov/pubmed/35304331
http://dx.doi.org/10.1016/j.molmet.2022.101472

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