Long-Read RNA Sequencing Identifies Polyadenylation Elongation and Differential Transcript Usage of Host Transcripts During SARS-CoV-2 In Vitro Infection

Better methods to interrogate host-pathogen interactions during Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infections are imperative to help understand and prevent this disease. Here we implemented RNA-sequencing (RNA-seq) using Oxford Nanopore Technologies (ONT) long-reads to meas...

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Detalles Bibliográficos
Autores principales: Chang, Jessie J.-Y., Gleeson, Josie, Rawlinson, Daniel, De Paoli-Iseppi, Ricardo, Zhou, Chenxi, Mordant, Francesca L., Londrigan, Sarah L., Clark, Michael B., Subbarao, Kanta, Stinear, Timothy P., Coin, Lachlan J. M., Pitt, Miranda E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019466/
https://www.ncbi.nlm.nih.gov/pubmed/35464437
http://dx.doi.org/10.3389/fimmu.2022.832223

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