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Inflammation Affects Liver Function and the Metabolism of Voriconazole to Voriconazole-N-Oxide in Adult and Elderly Patients

Background: The inner association of inflammation with voriconazole (VCZ) metabolism has not been fully investigated. We intend to investigate the effects of inflammation on liver function, VCZ trough concentration (C(0)), C(0)/dose ratio and the ratio of VCZ to VCZ-N-oxide concentration (C(0)/C(N))...

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Detalles Bibliográficos
Autores principales:	Liang, Zaiming, Yu, Mingjie, Liu, Zhirui, Liu, Fang, Jia, Changsheng, Xiong, Lirong, Dai, Qing, Qin, Shiwei, Cheng, Lin, Sun, Fengjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019686/ https://www.ncbi.nlm.nih.gov/pubmed/35462904 http://dx.doi.org/10.3389/fphar.2022.835871

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