PEM-seq comprehensively quantifies DNA repair outcomes during gene-editing and DSB repair

The repair products of double-stranded DNA breaks (DSBs) are crucial for investigating the mechanism underlying DNA damage repair as well as evaluating the safety and efficiency of gene-editing; however, a comprehensively quantitative assay remains to be established. Here, we describe the step-by-st...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Yin, Jianhang, Gan, Tingting, Liu, Mengzhu, Xin, Changchang, Zhang, Weiwei, Hu, Jiazhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019705/
https://www.ncbi.nlm.nih.gov/pubmed/35462794
http://dx.doi.org/10.1016/j.xpro.2021.101088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019705/
https://www.ncbi.nlm.nih.gov/pubmed/35462794
http://dx.doi.org/10.1016/j.xpro.2021.101088

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