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PEM-seq comprehensively quantifies DNA repair outcomes during gene-editing and DSB repair
The repair products of double-stranded DNA breaks (DSBs) are crucial for investigating the mechanism underlying DNA damage repair as well as evaluating the safety and efficiency of gene-editing; however, a comprehensively quantitative assay remains to be established. Here, we describe the step-by-st...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019705/ https://www.ncbi.nlm.nih.gov/pubmed/35462794 http://dx.doi.org/10.1016/j.xpro.2021.101088 |