CD47 antibody protects mice from doxorubicin-induced myocardial damage by suppressing cardiomyocyte apoptosis

Cluster of differentiation 47 (CD47) is upregulated in mouse models of doxorubicin (Dox)-induced dilated cardiomyopathy (DCM). To explore the role of CD47 in the development of DCM, in the present study, CD47 signaling was blocked by an anti-CD47 neutralizing antibody (aCD47) in mice with Dox-induce...

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Detalles Bibliográficos
Autores principales: Hao, Yan, Chen, Lianghua, Jiang, Zhilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019770/
https://www.ncbi.nlm.nih.gov/pubmed/35493436
http://dx.doi.org/10.3892/etm.2022.11277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019770/
https://www.ncbi.nlm.nih.gov/pubmed/35493436
http://dx.doi.org/10.3892/etm.2022.11277

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