Cargando…

The Molecular Basis of the Effect of Temperature on the Structure and Function of SARS-CoV-2 Spike Protein

The remarkable rise of the current COVID-19 pandemic to every part of the globe has raised key concerns for the current public healthcare system. The spike (S) protein of SARS-CoV-2 shows an important part in the cell membrane fusion and receptor recognition. It is a key target for vaccine productio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khan, Faez Iqbal, Lobb, Kevin A., Lai, Dakun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019816/ https://www.ncbi.nlm.nih.gov/pubmed/35463957 http://dx.doi.org/10.3389/fmolb.2022.794960

Ejemplares similares

Investigation of the Effect of Temperature on the Structure of SARS-CoV-2 Spike Protein by Molecular Dynamics Simulations
por: Rath, Soumya Lipsa, et al.
Publicado: (2020)

The Physical Basis for pH Sensitivity in Biomolecular Structure and Function, With Application to the Spike Protein of SARS-CoV-2
por: Warwicker, Jim
Publicado: (2022)

Spike Proteins of SARS-CoV and SARS-CoV-2 Utilize Different Mechanisms to Bind With Human ACE2
por: Xie, Yixin, et al.
Publicado: (2020)

Computational Saturation Mutagenesis of SARS-CoV-1 Spike Glycoprotein: Stability, Binding Affinity, and Comparison With SARS-CoV-2
por: Sobitan, Adebiyi, et al.
Publicado: (2021)

SARS-CoV-2 Spike Protein Extrapolation for COVID Diagnosis and Vaccine Development
por: Malik, Yashpal S., et al.
Publicado: (2021)

Glycans of SARS-CoV-2 Spike Protein in Virus Infection and Antibody Production
por: Zhao, Xiaohui, et al.
Publicado: (2021)

DNA Aptamers Block the Receptor Binding Domain at the Spike Protein of SARS-CoV-2
por: Cleri, Fabrizio, et al.
Publicado: (2021)

Cytoplasmic tail determines the membrane trafficking and localization of SARS-CoV-2 spike protein
por: Li, Qinlin, et al.
Publicado: (2022)

Molecular Docking and Dynamics Studies to Explore Effective Inhibitory Peptides Against the Spike Receptor Binding Domain of SARS-CoV-2
por: Biswas, Suvro, et al.
Publicado: (2022)

Shape Complementarity Optimization of Antibody–Antigen Interfaces: The Application to SARS-CoV-2 Spike Protein
por: De Lauro, Alfredo, et al.
Publicado: (2022)

Non-RBM Mutations Impaired SARS-CoV-2 Spike Protein Regulated to the ACE2 Receptor Based on Molecular Dynamic Simulation
por: Du, Yaoqiang, et al.
Publicado: (2021)

In Silico Studies on Psilocybin Drug Derivatives Against SARS-CoV-2 and Cytokine Storm of Human Interleukin-6 Receptor
por: Khan, Faez Iqbal, et al.
Publicado: (2022)

Synthesis and Cytotoxic Activity of Novel Indole Derivatives and Their in silico Screening on Spike Glycoprotein of SARS-CoV-2
por: Gobinath, Perumal, et al.
Publicado: (2021)

Host Cell Glycocalyx Remodeling Reveals SARS-CoV-2 Spike Protein Glycomic Binding Sites
por: Sheng, Ying, et al.
Publicado: (2022)

Biochemical Characterization of SARS-CoV-2 Spike RBD Mutations and Their Impact on ACE2 Receptor Binding
por: Hoter, Abdullah, et al.
Publicado: (2022)

Interactions between heparin and SARS-CoV-2 spike glycoprotein RBD from omicron and other variants
por: Gelbach, Adrianne L., et al.
Publicado: (2022)

Differences in the organization of interface residues tunes the stability of the SARS-CoV-2 spike-ACE2 complex
por: Miotto, Mattia, et al.
Publicado: (2023)

Heparan Sulfate Facilitates Spike Protein-Mediated SARS-CoV-2 Host Cell Invasion and Contributes to Increased Infection of SARS-CoV-2 G614 Mutant and in Lung Cancer
por: Yue, Jingwen, et al.
Publicado: (2021)

Remdesivir Strongly Binds to RNA-Dependent RNA Polymerase, Membrane Protein, and Main Protease of SARS-CoV-2: Indication From Molecular Modeling and Simulations
por: Khan, Faez Iqbal, et al.
Publicado: (2021)

Corrigendum: Synthesis and Cytotoxic Activity of Novel Indole Derivatives and Their in silico Screening on Spike Glycoprotein of SARS-CoV-2
por: Gobinath, Perumal, et al.
Publicado: (2021)

A Strategy Based on Loop Analysis to Develop Peptide Epitopes: Application to SARS-CoV-2 Spike Protein
por: Di Vona, Maria Luisa, et al.
Publicado: (2021)

Molecular Mechanisms Behind Anti SARS-CoV-2 Action of Lactoferrin
por: Miotto, Mattia, et al.
Publicado: (2021)

Surveying the Side-Chain Network Approach to Protein Structure and Dynamics: The SARS-CoV-2 Spike Protein as an Illustrative Case
por: Halder, Anushka, et al.
Publicado: (2020)

In silico Screening of Natural Compounds as Potential Inhibitors of SARS-CoV-2 Main Protease and Spike RBD: Targets for COVID-19
por: Teli, Divya M., et al.
Publicado: (2021)

Computational Insights Into the Effects of the R190K and N121Q Mutations on the SARS-CoV-2 Spike Complex With Biliverdin
por: Qu, Zhiyuan, et al.
Publicado: (2021)

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
por: Ahmed, Wesam S., et al.
Publicado: (2022)

Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex
por: Ahmed, Wesam S., et al.
Publicado: (2022)

SARS-CoV-2 and Glutamine: SARS-CoV-2 Triggered Pathogenesis via Metabolic Reprograming of Glutamine in Host Cells
por: Bharadwaj, Shiv, et al.
Publicado: (2021)

Improvement of native structure-based peptides as efficient inhibitors of protein-protein interactions of SARS-CoV-2 spike protein and human ACE2
por: Odolczyk, Norbert, et al.
Publicado: (2022)

SARS-CoV-2 UK, South African and Brazilian Variants in Karachi- Pakistan
por: Khan, Adnan, et al.
Publicado: (2021)

SARS-CoV-2 Spike Protein Unlikely to Bind to Integrins via the Arg-Gly-Asp (RGD) Motif of the Receptor Binding Domain: Evidence From Structural Analysis and Microscale Accelerated Molecular Dynamics
por: Othman, Houcemeddine, et al.
Publicado: (2022)

SARS-CoV-2 Virion Stabilization by Zn Binding
por: Morante, Silvia, et al.
Publicado: (2020)

Drug Weaponry to Fight Against SARS-CoV-2
por: Cabezón, Elena, et al.
Publicado: (2020)

Antibodies and Vaccines Target RBD of SARS-CoV-2
por: Min, Long, et al.
Publicado: (2021)

Modeling of the thermal properties of SARS-CoV-2 S-protein
por: Niu, Ziyuan, et al.
Publicado: (2022)

Potent Molecular Feature-based Neutralizing Monoclonal Antibodies as Promising Therapeutics Against SARS-CoV-2 Infection
por: Kombe Kombe, Arnaud John, et al.
Publicado: (2021)

Refinement of SARS-CoV-2 envelope protein structure in a native-like environment by molecular dynamics simulations
por: Yang, Rui, et al.
Publicado: (2022)

Circulating Exosomes Are Strongly Involved in SARS-CoV-2 Infection
por: Barberis, Elettra, et al.
Publicado: (2021)

Immune Response in Myocardial Injury: In Situ Hybridization and Immunohistochemistry Techniques for SARS-CoV-2 Detection in COVID-19 Autopsies
por: Chong, Pek Yoon, et al.
Publicado: (2021)

Editorial: Interaction of Biomolecules and Bioactive Compounds With the SARS-CoV-2 Proteins: Molecular Simulations for the Fight Against Covid-19
por: Falconi, Mattia, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_fic82o7u950bjbrbtqf5i901iu