Impact of APOE genotype on prion-type propagation of tauopathy

Apolipoprotein (APOE) is a major risk factor of Alzheimer’s disease (AD), with the E2, E3 and E4 isoforms differentially regulating the burden of AD-associated neuropathologies, such as amyloid β and tau. In AD, pathological tau is thought to spread along neuroanatomic connections following a prion-...

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Detalles Bibliográficos
Autores principales: Williams, Tristan, Ruiz, Alejandra Jolie, Ruiz, Angelica Maria, Vo, Quan, Tsering, Wangchen, Xu, Guilian, McFarland, Karen, Giasson, Benoit I., Sullivan, Patrick, Borchelt, David R., Chakrabarty, Paramita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019935/
https://www.ncbi.nlm.nih.gov/pubmed/35440098
http://dx.doi.org/10.1186/s40478-022-01359-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019935/
https://www.ncbi.nlm.nih.gov/pubmed/35440098
http://dx.doi.org/10.1186/s40478-022-01359-y

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