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Association among calf circumference, physical performance, and depression in the elderly Chinese population: a cross-sectional study

BACKGROUND: Depression and sarcopenia are common diseases in the elderly population. However, the association between them is controversial. Based on the Chinese Longitudinal Healthy Longevity Survey (CLHLS) database, a cross-sectional study was conducted to explore the relationship of calf circumfe...

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Autores principales: Tan, Jian-Yu, Zeng, Qing-Lian, Ni, Meng, Zhang, Ying-Xiao, Qiu, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020001/
https://www.ncbi.nlm.nih.gov/pubmed/35443643
http://dx.doi.org/10.1186/s12888-022-03925-z
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author Tan, Jian-Yu
Zeng, Qing-Lian
Ni, Meng
Zhang, Ying-Xiao
Qiu, Tian
author_facet Tan, Jian-Yu
Zeng, Qing-Lian
Ni, Meng
Zhang, Ying-Xiao
Qiu, Tian
author_sort Tan, Jian-Yu
collection PubMed
description BACKGROUND: Depression and sarcopenia are common diseases in the elderly population. However, the association between them is controversial. Based on the Chinese Longitudinal Healthy Longevity Survey (CLHLS) database, a cross-sectional study was conducted to explore the relationship of calf circumference and physical performance with depression. METHODS: From the 8th wave of CLHLS conducted in 2018, data on calf circumference, physical performance, depressive symptoms, and demographic, socioeconomic, and health-related characteristics were collected. Multiple logistic regression was conducted to explore the impact of calf circumference, physical performance and their combination on depressive symptoms. RESULTS: We enrolled a total of 12,227 participants aged 83.4 ± 11.0 years, including 5689 (46.5%) men and 6538 (53.5%) women. Patients with depression were more likely to have low calf circumference (2274 [68.2%] vs. 5406 [60.8%], p<0.001) and poor physical performance (3[0, 6] vs. 1[0, 4], p<0.001). A significant multiplicative interaction was found between calf circumference and physical performance in their effect on depression. After adjusting for confounding factors, multiple logistic regression showed that a significant inverse correlation persisted between physical performance and depressive symptoms in normal (odds ratio [OR] = 1.20, 95% confidence interval [CI]: 1.15–1.26, p<0.001) and low (OR = 1.14, 95% CI: 1.11–1.18, p<0.001) calf circumference group, while the association between calf circumference and depression disappeared. Participants with low calf circumference and poor physical performance were 2.21 times more likely to have depression than those with normal calf circumference and physical performance. All results were found to be robust in sensitivity analyses. CONCLUSIONS: Physical performance was significantly associated with depression in the elderly Chinese population. Attention should be paid to assess depressive symptoms in patients with poor physical performance. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12888-022-03925-z.
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spelling pubmed-90200012022-04-21 Association among calf circumference, physical performance, and depression in the elderly Chinese population: a cross-sectional study Tan, Jian-Yu Zeng, Qing-Lian Ni, Meng Zhang, Ying-Xiao Qiu, Tian BMC Psychiatry Research BACKGROUND: Depression and sarcopenia are common diseases in the elderly population. However, the association between them is controversial. Based on the Chinese Longitudinal Healthy Longevity Survey (CLHLS) database, a cross-sectional study was conducted to explore the relationship of calf circumference and physical performance with depression. METHODS: From the 8th wave of CLHLS conducted in 2018, data on calf circumference, physical performance, depressive symptoms, and demographic, socioeconomic, and health-related characteristics were collected. Multiple logistic regression was conducted to explore the impact of calf circumference, physical performance and their combination on depressive symptoms. RESULTS: We enrolled a total of 12,227 participants aged 83.4 ± 11.0 years, including 5689 (46.5%) men and 6538 (53.5%) women. Patients with depression were more likely to have low calf circumference (2274 [68.2%] vs. 5406 [60.8%], p<0.001) and poor physical performance (3[0, 6] vs. 1[0, 4], p<0.001). A significant multiplicative interaction was found between calf circumference and physical performance in their effect on depression. After adjusting for confounding factors, multiple logistic regression showed that a significant inverse correlation persisted between physical performance and depressive symptoms in normal (odds ratio [OR] = 1.20, 95% confidence interval [CI]: 1.15–1.26, p<0.001) and low (OR = 1.14, 95% CI: 1.11–1.18, p<0.001) calf circumference group, while the association between calf circumference and depression disappeared. Participants with low calf circumference and poor physical performance were 2.21 times more likely to have depression than those with normal calf circumference and physical performance. All results were found to be robust in sensitivity analyses. CONCLUSIONS: Physical performance was significantly associated with depression in the elderly Chinese population. Attention should be paid to assess depressive symptoms in patients with poor physical performance. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12888-022-03925-z. BioMed Central 2022-04-20 /pmc/articles/PMC9020001/ /pubmed/35443643 http://dx.doi.org/10.1186/s12888-022-03925-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Tan, Jian-Yu
Zeng, Qing-Lian
Ni, Meng
Zhang, Ying-Xiao
Qiu, Tian
Association among calf circumference, physical performance, and depression in the elderly Chinese population: a cross-sectional study
title Association among calf circumference, physical performance, and depression in the elderly Chinese population: a cross-sectional study
title_full Association among calf circumference, physical performance, and depression in the elderly Chinese population: a cross-sectional study
title_fullStr Association among calf circumference, physical performance, and depression in the elderly Chinese population: a cross-sectional study
title_full_unstemmed Association among calf circumference, physical performance, and depression in the elderly Chinese population: a cross-sectional study
title_short Association among calf circumference, physical performance, and depression in the elderly Chinese population: a cross-sectional study
title_sort association among calf circumference, physical performance, and depression in the elderly chinese population: a cross-sectional study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020001/
https://www.ncbi.nlm.nih.gov/pubmed/35443643
http://dx.doi.org/10.1186/s12888-022-03925-z
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