Intracellular marriage of bicarbonate and Mn ions as “immune ion reactors” to regulate redox homeostasis and enhanced antitumor immune responses

BACKGROUND: Different from Fe ions in Fenton reaction, Mn ions can function both as catalyst for chemodynamic therapy and immune adjuvant for antitumor immune responses. In Mn-mediated Fenton-like reaction, bicarbonate ([Formula: see text] ), as the most important component to amplify therapeutic ef...

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Detalles Bibliográficos
Autores principales: Feng, Yushuo, Liu, Yaqing, Ma, Xiaoqian, Xu, Lihua, Ding, Dandan, Chen, Lei, Wang, Zongzhang, Qin, Ruixue, Sun, Wenjing, Chen, Hongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020034/
https://www.ncbi.nlm.nih.gov/pubmed/35440088
http://dx.doi.org/10.1186/s12951-022-01404-x

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