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De novo identification of maximally deregulated subnetworks based on multi-omics data with DeRegNet

BACKGROUND: With a growing amount of (multi-)omics data being available, the extraction of knowledge from these datasets is still a difficult problem. Classical enrichment-style analyses require predefined pathways or gene sets that are tested for significant deregulation to assess whether the pathw...

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Detalles Bibliográficos
Autores principales: Winkler, Sebastian, Winkler, Ivana, Figaschewski, Mirjam, Tiede, Thorsten, Nordheim, Alfred, Kohlbacher, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020058/
https://www.ncbi.nlm.nih.gov/pubmed/35439941
http://dx.doi.org/10.1186/s12859-022-04670-6

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