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CT-707 overcomes hypoxia-mediated sorafenib resistance in Hepatocellular carcinoma by inhibiting YAP signaling

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths worldwide. Sorafenib is the first-line treatment for advanced HCC, but the anti-cancer effects remain to be improved as indicated by its low response rates and failure to prolong the progression-free sur...

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Detalles Bibliográficos
Autores principales:	Chen, Zibo, Yuan, Tao, Yan, Fangjie, Ye, Song, Xie, Qin, Zhang, Bo, Lin, Nengmin, He, Qiaojun, Yang, Bo, Zhu, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020089/ https://www.ncbi.nlm.nih.gov/pubmed/35440025 http://dx.doi.org/10.1186/s12885-022-09520-5

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