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The potential of using itaconate as treatment for inflammation-related heart diseases

Intracellular metabolites can cause critical changes in biological functions. Itaconate is perhaps the most fascinating substance in macrophages. Lipopolysaccharide can activate aconitate decarboxylase 1 and induces the generation of itaconate from the tricarboxylic acid cycle by decarboxylation of...

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Detalles Bibliográficos
Autores principales: Ku, Hui-Chen, Shen, Ta-Chung, Cheng, Ching-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020236/
https://www.ncbi.nlm.nih.gov/pubmed/35465278
http://dx.doi.org/10.4103/tcmj.tcmj_83_21

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