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Identification of the Transgene Integration Site and Host Genome Changes in MRP8-Cre/ires-EGFP Transgenic Mice by Targeted Locus Amplification

The MRP8-Cre-ires/EGFP transgenic mouse (Mrp8cre(Tg), on C57BL/6J genetic background) is popular in immunological and hematological research for specifically expressing Cre recombinase and an EGFP reporter in neutrophils. It is often crossed with other transgenic lines carrying loxP-flanked genes to...

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Detalles Bibliográficos
Autores principales: Wang, Guan, Zhang, Cunling, Kambara, Hiroto, Dambrot, Cheryl, Xie, Xuemei, Zhao, Li, Xu, Rong, Oneglia, Andrea, Liu, Fei, Luo, Hongbo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020256/
https://www.ncbi.nlm.nih.gov/pubmed/35464448
http://dx.doi.org/10.3389/fimmu.2022.875991

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