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Development and validation of a prognostic nomogram for open elbow arthrolysis: the Shanghai Prediction model for Elbow Stiffness Surgical Outcome
AIMS: The aim of this study was to develop and internally validate a prognostic nomogram to predict the probability of gaining a functional range of motion (ROM ≥ 120°) after open arthrolysis of the elbow in patients with post-traumatic stiffness of the elbow. METHODS: We developed the Shanghai Pred...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The British Editorial Society of Bone & Joint Surgery
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020519/ https://www.ncbi.nlm.nih.gov/pubmed/35360939 http://dx.doi.org/10.1302/0301-620X.104B4.BJJ-2021-1326.R2 |
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author | Liu, Weixuan Sun, Ziyang Xiong, Hao Liu, Junjian Lu, Jiuzhou Cai, Bin Wang, Wei Fan, Cunyi |
author_facet | Liu, Weixuan Sun, Ziyang Xiong, Hao Liu, Junjian Lu, Jiuzhou Cai, Bin Wang, Wei Fan, Cunyi |
author_sort | Liu, Weixuan |
collection | PubMed |
description | AIMS: The aim of this study was to develop and internally validate a prognostic nomogram to predict the probability of gaining a functional range of motion (ROM ≥ 120°) after open arthrolysis of the elbow in patients with post-traumatic stiffness of the elbow. METHODS: We developed the Shanghai Prediction Model for Elbow Stiffness Surgical Outcome (SPESSO) based on a dataset of 551 patients who underwent open arthrolysis of the elbow in four institutions. Demographic and clinical characteristics were collected from medical records. The least absolute shrinkage and selection operator regression model was used to optimize the selection of relevant features. Multivariable logistic regression analysis was used to build the SPESSO. Its prediction performance was evaluated using the concordance index (C-index) and a calibration graph. Internal validation was conducted using bootstrapping validation. RESULTS: BMI, the duration of stiffness, the preoperative ROM, the preoperative intensity of pain, and grade of post-traumatic osteoarthritis of the elbow were identified as predictors of outcome and incorporated to construct the nomogram. SPESSO displayed good discrimination with a C-index of 0.73 (95% confidence interval 0.64 to 0.81). A high C-index value of 0.70 could still be reached in the interval validation. The calibration graph showed good agreement between the nomogram prediction and the outcome. CONCLUSION: The newly developed SPESSO is a valid and convenient model which can be used to predict the outcome of open arthrolysis of the elbow. It could assist clinicians in counselling patients regarding the choice and expectations of treatment. Cite this article: Bone Joint J 2022;104-B(4):486–494. |
format | Online Article Text |
id | pubmed-9020519 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The British Editorial Society of Bone & Joint Surgery |
record_format | MEDLINE/PubMed |
spelling | pubmed-90205192022-05-03 Development and validation of a prognostic nomogram for open elbow arthrolysis: the Shanghai Prediction model for Elbow Stiffness Surgical Outcome Liu, Weixuan Sun, Ziyang Xiong, Hao Liu, Junjian Lu, Jiuzhou Cai, Bin Wang, Wei Fan, Cunyi Bone Joint J Shoulder & Elbow AIMS: The aim of this study was to develop and internally validate a prognostic nomogram to predict the probability of gaining a functional range of motion (ROM ≥ 120°) after open arthrolysis of the elbow in patients with post-traumatic stiffness of the elbow. METHODS: We developed the Shanghai Prediction Model for Elbow Stiffness Surgical Outcome (SPESSO) based on a dataset of 551 patients who underwent open arthrolysis of the elbow in four institutions. Demographic and clinical characteristics were collected from medical records. The least absolute shrinkage and selection operator regression model was used to optimize the selection of relevant features. Multivariable logistic regression analysis was used to build the SPESSO. Its prediction performance was evaluated using the concordance index (C-index) and a calibration graph. Internal validation was conducted using bootstrapping validation. RESULTS: BMI, the duration of stiffness, the preoperative ROM, the preoperative intensity of pain, and grade of post-traumatic osteoarthritis of the elbow were identified as predictors of outcome and incorporated to construct the nomogram. SPESSO displayed good discrimination with a C-index of 0.73 (95% confidence interval 0.64 to 0.81). A high C-index value of 0.70 could still be reached in the interval validation. The calibration graph showed good agreement between the nomogram prediction and the outcome. CONCLUSION: The newly developed SPESSO is a valid and convenient model which can be used to predict the outcome of open arthrolysis of the elbow. It could assist clinicians in counselling patients regarding the choice and expectations of treatment. Cite this article: Bone Joint J 2022;104-B(4):486–494. The British Editorial Society of Bone & Joint Surgery 2022-04 2022-04-01 /pmc/articles/PMC9020519/ /pubmed/35360939 http://dx.doi.org/10.1302/0301-620X.104B4.BJJ-2021-1326.R2 Text en © 2022 Author(s) et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND 4.0) licence, which permits the copying and redistribution of the work only, and provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc-nd/4.0/ |
spellingShingle | Shoulder & Elbow Liu, Weixuan Sun, Ziyang Xiong, Hao Liu, Junjian Lu, Jiuzhou Cai, Bin Wang, Wei Fan, Cunyi Development and validation of a prognostic nomogram for open elbow arthrolysis: the Shanghai Prediction model for Elbow Stiffness Surgical Outcome |
title | Development and validation of a prognostic nomogram for open elbow arthrolysis: the Shanghai Prediction model for Elbow Stiffness Surgical Outcome |
title_full | Development and validation of a prognostic nomogram for open elbow arthrolysis: the Shanghai Prediction model for Elbow Stiffness Surgical Outcome |
title_fullStr | Development and validation of a prognostic nomogram for open elbow arthrolysis: the Shanghai Prediction model for Elbow Stiffness Surgical Outcome |
title_full_unstemmed | Development and validation of a prognostic nomogram for open elbow arthrolysis: the Shanghai Prediction model for Elbow Stiffness Surgical Outcome |
title_short | Development and validation of a prognostic nomogram for open elbow arthrolysis: the Shanghai Prediction model for Elbow Stiffness Surgical Outcome |
title_sort | development and validation of a prognostic nomogram for open elbow arthrolysis: the shanghai prediction model for elbow stiffness surgical outcome |
topic | Shoulder & Elbow |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020519/ https://www.ncbi.nlm.nih.gov/pubmed/35360939 http://dx.doi.org/10.1302/0301-620X.104B4.BJJ-2021-1326.R2 |
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