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Ad26.COV2.S prevents upregulation of SARS-CoV-2 induced pathways of inflammation and thrombosis in hamsters and rhesus macaques

Syrian golden hamsters exhibit features of severe disease after SARS-CoV-2 WA1/2020 challenge and are therefore useful models of COVID-19 pathogenesis and prevention with vaccines. Recent studies have shown that SARS-CoV-2 infection stimulates type I interferon, myeloid, and inflammatory signatures...

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Detalles Bibliográficos
Autores principales:	Aid, Malika, Vidal, Samuel J., Piedra-Mora, Cesar, Ducat, Sarah, Chan, Chi N., Bondoc, Stephen, Colarusso, Alessandro, Starke, Carly E., Nekorchuk, Michael, Busman-Sahay, Kathleen, Estes, Jacob D., Martinot, Amanda J., Barouch, Dan H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020736/ https://www.ncbi.nlm.nih.gov/pubmed/35395058 http://dx.doi.org/10.1371/journal.ppat.1009990

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