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Activity in perirhinal and entorhinal cortex predicts perceived visual similarities among category exemplars with highest precision
Vision neuroscience has made great strides in understanding the hierarchical organization of object representations along the ventral visual stream (VVS). How VVS representations capture fine-grained visual similarities between objects that observers subjectively perceive has received limited examin...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020819/ https://www.ncbi.nlm.nih.gov/pubmed/35311645 http://dx.doi.org/10.7554/eLife.66884 |
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author | Ferko, Kayla M Blumenthal, Anna Martin, Chris B Proklova, Daria Minos, Alexander N Saksida, Lisa M Bussey, Timothy J Khan, Ali R Köhler, Stefan |
author_facet | Ferko, Kayla M Blumenthal, Anna Martin, Chris B Proklova, Daria Minos, Alexander N Saksida, Lisa M Bussey, Timothy J Khan, Ali R Köhler, Stefan |
author_sort | Ferko, Kayla M |
collection | PubMed |
description | Vision neuroscience has made great strides in understanding the hierarchical organization of object representations along the ventral visual stream (VVS). How VVS representations capture fine-grained visual similarities between objects that observers subjectively perceive has received limited examination so far. In the current study, we addressed this question by focussing on perceived visual similarities among subordinate exemplars of real-world categories. We hypothesized that these perceived similarities are reflected with highest fidelity in neural activity patterns downstream from inferotemporal regions, namely in perirhinal (PrC) and anterolateral entorhinal cortex (alErC) in the medial temporal lobe. To address this issue with functional magnetic resonance imaging (fMRI), we administered a modified 1-back task that required discrimination between category exemplars as well as categorization. Further, we obtained observer-specific ratings of perceived visual similarities, which predicted behavioural discrimination performance during scanning. As anticipated, we found that activity patterns in PrC and alErC predicted the structure of perceived visual similarity relationships among category exemplars, including its observer-specific component, with higher precision than any other VVS region. Our findings provide new evidence that subjective aspects of object perception that rely on fine-grained visual differentiation are reflected with highest fidelity in the medial temporal lobe. |
format | Online Article Text |
id | pubmed-9020819 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | eLife Sciences Publications, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-90208192022-04-21 Activity in perirhinal and entorhinal cortex predicts perceived visual similarities among category exemplars with highest precision Ferko, Kayla M Blumenthal, Anna Martin, Chris B Proklova, Daria Minos, Alexander N Saksida, Lisa M Bussey, Timothy J Khan, Ali R Köhler, Stefan eLife Neuroscience Vision neuroscience has made great strides in understanding the hierarchical organization of object representations along the ventral visual stream (VVS). How VVS representations capture fine-grained visual similarities between objects that observers subjectively perceive has received limited examination so far. In the current study, we addressed this question by focussing on perceived visual similarities among subordinate exemplars of real-world categories. We hypothesized that these perceived similarities are reflected with highest fidelity in neural activity patterns downstream from inferotemporal regions, namely in perirhinal (PrC) and anterolateral entorhinal cortex (alErC) in the medial temporal lobe. To address this issue with functional magnetic resonance imaging (fMRI), we administered a modified 1-back task that required discrimination between category exemplars as well as categorization. Further, we obtained observer-specific ratings of perceived visual similarities, which predicted behavioural discrimination performance during scanning. As anticipated, we found that activity patterns in PrC and alErC predicted the structure of perceived visual similarity relationships among category exemplars, including its observer-specific component, with higher precision than any other VVS region. Our findings provide new evidence that subjective aspects of object perception that rely on fine-grained visual differentiation are reflected with highest fidelity in the medial temporal lobe. eLife Sciences Publications, Ltd 2022-03-21 /pmc/articles/PMC9020819/ /pubmed/35311645 http://dx.doi.org/10.7554/eLife.66884 Text en © 2022, Ferko et al https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Neuroscience Ferko, Kayla M Blumenthal, Anna Martin, Chris B Proklova, Daria Minos, Alexander N Saksida, Lisa M Bussey, Timothy J Khan, Ali R Köhler, Stefan Activity in perirhinal and entorhinal cortex predicts perceived visual similarities among category exemplars with highest precision |
title | Activity in perirhinal and entorhinal cortex predicts perceived visual similarities among category exemplars with highest precision |
title_full | Activity in perirhinal and entorhinal cortex predicts perceived visual similarities among category exemplars with highest precision |
title_fullStr | Activity in perirhinal and entorhinal cortex predicts perceived visual similarities among category exemplars with highest precision |
title_full_unstemmed | Activity in perirhinal and entorhinal cortex predicts perceived visual similarities among category exemplars with highest precision |
title_short | Activity in perirhinal and entorhinal cortex predicts perceived visual similarities among category exemplars with highest precision |
title_sort | activity in perirhinal and entorhinal cortex predicts perceived visual similarities among category exemplars with highest precision |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020819/ https://www.ncbi.nlm.nih.gov/pubmed/35311645 http://dx.doi.org/10.7554/eLife.66884 |
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