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Increased Expression of Prolyl Endopeptidase Induced by Oxidative Stress in Nucleus Pulposus Cells Aggravates Intervertebral Disc Degeneration

A healthy microenvironment of the intervertebral disc tissue is characterized by hypoxia owing to its sparse vascular distribution. Oxidative stress plays a pivotal role in the pathological development of intervertebral disc degeneration (IVDD). We found that the expression of prolyl endopeptidase (...

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Detalles Bibliográficos
Autores principales:	Zheng, Huo-Liang, Xu, Wen-Ning, Chen, Peng-Bo, Jiang, Lei-Sheng, Zheng, Xin-Feng, Jiang, Sheng-Dan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020979/ https://www.ncbi.nlm.nih.gov/pubmed/35464773 http://dx.doi.org/10.1155/2022/9731800

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