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A Rare Case of Embryonal Rhabdomyosarcoma of the Uterine Cervix

Embryonal rhabdomyosarcoma (RMS) of the uterine cervix is an exceedingly rare mesenchymal tumor that accounts for less than 1% of all cervical cancers. This highly malignant tumor primarily affects adolescents and young adults. Due to the paucity of publications on this clinical entity, there are no...

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Autores principales: Bahall, Vishal, De Barry, Lance, Sankar, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020987/
https://www.ncbi.nlm.nih.gov/pubmed/35464884
http://dx.doi.org/10.1155/2022/8459566
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author Bahall, Vishal
De Barry, Lance
Sankar, Steven
author_facet Bahall, Vishal
De Barry, Lance
Sankar, Steven
author_sort Bahall, Vishal
collection PubMed
description Embryonal rhabdomyosarcoma (RMS) of the uterine cervix is an exceedingly rare mesenchymal tumor that accounts for less than 1% of all cervical cancers. This highly malignant tumor primarily affects adolescents and young adults. Due to the paucity of publications on this clinical entity, there are no clearly established treatment protocols. However, a multimodal approach to treatment that involves surgical intervention combined with adjuvant chemoradiotherapy appears to improve patient outcomes. Herein, we report a case of embryonal rhabdomyosarcoma of the uterine cervix in a 24-year-old female, who presented with an exophytic cervical mass and vaginal bleeding. Histopathology and immunohistochemistry confirmed embryonal rhabdomyosarcoma of the uterine cervix with extension into the lower uterine segment. This patient was successfully managed with a combination of neoadjuvant chemoradiotherapy, a total abdominal hysterectomy with bilateral salpingo-oophorectomy, and adjuvant chemoradiotherapy.
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spelling pubmed-90209872022-04-21 A Rare Case of Embryonal Rhabdomyosarcoma of the Uterine Cervix Bahall, Vishal De Barry, Lance Sankar, Steven Case Rep Pathol Case Report Embryonal rhabdomyosarcoma (RMS) of the uterine cervix is an exceedingly rare mesenchymal tumor that accounts for less than 1% of all cervical cancers. This highly malignant tumor primarily affects adolescents and young adults. Due to the paucity of publications on this clinical entity, there are no clearly established treatment protocols. However, a multimodal approach to treatment that involves surgical intervention combined with adjuvant chemoradiotherapy appears to improve patient outcomes. Herein, we report a case of embryonal rhabdomyosarcoma of the uterine cervix in a 24-year-old female, who presented with an exophytic cervical mass and vaginal bleeding. Histopathology and immunohistochemistry confirmed embryonal rhabdomyosarcoma of the uterine cervix with extension into the lower uterine segment. This patient was successfully managed with a combination of neoadjuvant chemoradiotherapy, a total abdominal hysterectomy with bilateral salpingo-oophorectomy, and adjuvant chemoradiotherapy. Hindawi 2022-04-13 /pmc/articles/PMC9020987/ /pubmed/35464884 http://dx.doi.org/10.1155/2022/8459566 Text en Copyright © 2022 Vishal Bahall et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Bahall, Vishal
De Barry, Lance
Sankar, Steven
A Rare Case of Embryonal Rhabdomyosarcoma of the Uterine Cervix
title A Rare Case of Embryonal Rhabdomyosarcoma of the Uterine Cervix
title_full A Rare Case of Embryonal Rhabdomyosarcoma of the Uterine Cervix
title_fullStr A Rare Case of Embryonal Rhabdomyosarcoma of the Uterine Cervix
title_full_unstemmed A Rare Case of Embryonal Rhabdomyosarcoma of the Uterine Cervix
title_short A Rare Case of Embryonal Rhabdomyosarcoma of the Uterine Cervix
title_sort rare case of embryonal rhabdomyosarcoma of the uterine cervix
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020987/
https://www.ncbi.nlm.nih.gov/pubmed/35464884
http://dx.doi.org/10.1155/2022/8459566
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