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Risk Factors for Coronary Heart Disease Among Lebanese Women: A Case–Control Study

PURPOSE: Women are increasingly concerned by coronary heart disease (CHD), with peculiarities of their own, particularly concerning risk factors. The aim of the study was to assess the risk factors for CHD in Lebanese women over forty. PATIENTS AND METHODS: A case–control study was carried out in 6...

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Autores principales: Ghaddar, Fatima, Zeidan, Rouba K, Salameh, Pascale, Tatari, Souzan, Achkouty, Guy, Maupas-Schwalm, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021001/
https://www.ncbi.nlm.nih.gov/pubmed/35464735
http://dx.doi.org/10.2147/VHRM.S350108
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author Ghaddar, Fatima
Zeidan, Rouba K
Salameh, Pascale
Tatari, Souzan
Achkouty, Guy
Maupas-Schwalm, Françoise
author_facet Ghaddar, Fatima
Zeidan, Rouba K
Salameh, Pascale
Tatari, Souzan
Achkouty, Guy
Maupas-Schwalm, Françoise
author_sort Ghaddar, Fatima
collection PubMed
description PURPOSE: Women are increasingly concerned by coronary heart disease (CHD), with peculiarities of their own, particularly concerning risk factors. The aim of the study was to assess the risk factors for CHD in Lebanese women over forty. PATIENTS AND METHODS: A case–control study was carried out in 6 hospitals in Beirut and Mount-Lebanon, from December 2018 to December 2019 including 1500 patients (1200 controls and 300 cases). Women were stratified into pre- and post-menopausal groups. Personal and medical data were collected from hospital records and during an interview where validated questionnaires were used. Binary logistic regressions were performed to investigate potential predictors of CHD in the 2 groups. RESULTS: In post-menopausal women, dyslipidemia (adjusted odds ratio [aOR], 3.018; 95% confidence interval, 2.102–4.332), hypertension (aOR: 2.449, [1.386–4.327]), a family history of CHD (aOR: 2.724, [1.949–3.808]), cigarette smoking (aOR: 2.317, [1.574–3.410]) and common non-rheumatic joint pain (aOR: 1.457, [1.053–2.016]) were strongly associated with CHD. Conversely, living in Mount Lebanon seemed protective, compared to Beirut (aOR: 0.589, [0.406–0.854]), as well as having a moderate monthly income (aOR: 0.450, [0.220–0.923]), adhering to a Mediterranean diet (aOR: 0.965, [0.936–0.994]), and practicing physical activity [PA] (aOR: 0.396, [0.206–0.759] and 0.725, [0.529–0.992], respectively for high and moderate vs low PA). In pre-menopausal women, dyslipidemia (aOR: 6.938, [1.835–26.224]), hypertension (aOR: 6.195, [1.318–29.119]), family histories of dyslipidemia (aOR: 6.143, [1.560–24.191]) and CHD (aOR: 4.739, [1.336–16.805]) reached statistical significance. CONCLUSION: The identification of factors associated with CHD in women, some of which are frequent and trivialized in post-menopause, underlines the need to put in place specific and dedicated CHD prevention strategies in women.
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spelling pubmed-90210012022-04-21 Risk Factors for Coronary Heart Disease Among Lebanese Women: A Case–Control Study Ghaddar, Fatima Zeidan, Rouba K Salameh, Pascale Tatari, Souzan Achkouty, Guy Maupas-Schwalm, Françoise Vasc Health Risk Manag Original Research PURPOSE: Women are increasingly concerned by coronary heart disease (CHD), with peculiarities of their own, particularly concerning risk factors. The aim of the study was to assess the risk factors for CHD in Lebanese women over forty. PATIENTS AND METHODS: A case–control study was carried out in 6 hospitals in Beirut and Mount-Lebanon, from December 2018 to December 2019 including 1500 patients (1200 controls and 300 cases). Women were stratified into pre- and post-menopausal groups. Personal and medical data were collected from hospital records and during an interview where validated questionnaires were used. Binary logistic regressions were performed to investigate potential predictors of CHD in the 2 groups. RESULTS: In post-menopausal women, dyslipidemia (adjusted odds ratio [aOR], 3.018; 95% confidence interval, 2.102–4.332), hypertension (aOR: 2.449, [1.386–4.327]), a family history of CHD (aOR: 2.724, [1.949–3.808]), cigarette smoking (aOR: 2.317, [1.574–3.410]) and common non-rheumatic joint pain (aOR: 1.457, [1.053–2.016]) were strongly associated with CHD. Conversely, living in Mount Lebanon seemed protective, compared to Beirut (aOR: 0.589, [0.406–0.854]), as well as having a moderate monthly income (aOR: 0.450, [0.220–0.923]), adhering to a Mediterranean diet (aOR: 0.965, [0.936–0.994]), and practicing physical activity [PA] (aOR: 0.396, [0.206–0.759] and 0.725, [0.529–0.992], respectively for high and moderate vs low PA). In pre-menopausal women, dyslipidemia (aOR: 6.938, [1.835–26.224]), hypertension (aOR: 6.195, [1.318–29.119]), family histories of dyslipidemia (aOR: 6.143, [1.560–24.191]) and CHD (aOR: 4.739, [1.336–16.805]) reached statistical significance. CONCLUSION: The identification of factors associated with CHD in women, some of which are frequent and trivialized in post-menopause, underlines the need to put in place specific and dedicated CHD prevention strategies in women. Dove 2022-04-16 /pmc/articles/PMC9021001/ /pubmed/35464735 http://dx.doi.org/10.2147/VHRM.S350108 Text en © 2022 Ghaddar et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Ghaddar, Fatima
Zeidan, Rouba K
Salameh, Pascale
Tatari, Souzan
Achkouty, Guy
Maupas-Schwalm, Françoise
Risk Factors for Coronary Heart Disease Among Lebanese Women: A Case–Control Study
title Risk Factors for Coronary Heart Disease Among Lebanese Women: A Case–Control Study
title_full Risk Factors for Coronary Heart Disease Among Lebanese Women: A Case–Control Study
title_fullStr Risk Factors for Coronary Heart Disease Among Lebanese Women: A Case–Control Study
title_full_unstemmed Risk Factors for Coronary Heart Disease Among Lebanese Women: A Case–Control Study
title_short Risk Factors for Coronary Heart Disease Among Lebanese Women: A Case–Control Study
title_sort risk factors for coronary heart disease among lebanese women: a case–control study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021001/
https://www.ncbi.nlm.nih.gov/pubmed/35464735
http://dx.doi.org/10.2147/VHRM.S350108
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