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Whole genome sequencing-based drug resistance predictions of multidrug-resistant Mycobacterium tuberculosis isolates from Tanzania

BACKGROUND: Rifampicin- or multidrug-resistant (RR/MDR) Mycobacterium tuberculosis complex (MTBC) strains account for considerable morbidity and mortality globally. WGS-based prediction of drug resistance may guide clinical decisions, especially for the design of RR/MDR-TB therapies. METHODS: We com...

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Detalles Bibliográficos
Autores principales: Mbelele, Peter M., Utpatel, Christian, Sauli, Elingarami, Mpolya, Emmanuel A., Mutayoba, Beatrice K., Barilar, Ivan, Dreyer, Viola, Merker, Matthias, Sariko, Margaretha L., Swema, Buliga M., Mmbaga, Blandina T., Gratz, Jean, Addo, Kennedy K., Pletschette, Michel, Niemann, Stefan, Houpt, Eric R., Mpagama, Stellah G., Heysell, Scott K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021016/
https://www.ncbi.nlm.nih.gov/pubmed/35465240
http://dx.doi.org/10.1093/jacamr/dlac042