Single HER2-positive tumor cells are detected in initially HER2-negative breast carcinomas using the DEPArray™–HER2-FISH workflow

BACKGROUND: In breast cancer (BC), overexpression of HER2 on the primary tumor (PT) is determined by immunohistochemistry (IHC) or fluorescence in situ hybridization (FISH) to stratify samples as negative, equivocal and positive to identify patients (pts) for anti-HER2 therapy. CAP/ASCO guidelines r...

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Detalles Bibliográficos
Autores principales: Grüntkemeier, Lisa, Khurana, Aditi, Bischoff, Farideh Zamaniyan, Hoffmann, Oliver, Kimmig, Rainer, Moore, Mathew, Cotter, Philip, Kasimir-Bauer, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021056/
https://www.ncbi.nlm.nih.gov/pubmed/35025065
http://dx.doi.org/10.1007/s12282-022-01330-8

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