Salt-Inducible Kinase 1 is a potential therapeutic target in Desmoplastic Small Round Cell Tumor

Desmoplastic Small Round Cell Tumor (DSRCT) is a rare and aggressive malignant cancer caused by a chromosomal translocation t(11;22)(p13;q12) that produces an oncogenic transcription factor, EWSR1-WT1. EWSR1-WT1 is essential for the initiation and progression of DSRCT. However, the precise mechanism...

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Detalles Bibliográficos
Autores principales: Hartono, Alifiani Bonita, Kang, Hong-Jun, Shi, Lawrence, Phipps, Whitney, Ungerleider, Nathan, Giardina, Alexandra, Chen, WeiPing, Spraggon, Lee, Somwar, Romel, Moroz, Krzysztof, Drewry, David H., Burow, Matthew E., Flemington, Erik, Ladanyi, Marc, Lee, Sean Bong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021191/
https://www.ncbi.nlm.nih.gov/pubmed/35443736
http://dx.doi.org/10.1038/s41389-022-00395-6

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