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Restoration of ER proteostasis attenuates remote apoptotic cell death after spinal cord injury by reducing autophagosome overload

The pathogenic mechanisms that underlie the progression of remote degeneration after spinal cord injury (SCI) are not fully understood. In this study, we examined the relationship between endoplasmic reticulum (ER) stress and macroautophagy, hereafter autophagy, and its contribution to the secondary...

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Detalles Bibliográficos
Autores principales: Bisicchia, Elisa, Mastrantonio, Roberta, Nobili, Annalisa, Palazzo, Claudia, La Barbera, Livia, Latini, Laura, Millozzi, Francesco, Sasso, Valeria, Palacios, Daniela, D’Amelio, Marcello, Viscomi, Maria Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021197/
https://www.ncbi.nlm.nih.gov/pubmed/35444186
http://dx.doi.org/10.1038/s41419-022-04830-9