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Differential routing and disposition of the long-chain saturated fatty acid palmitate in rodent vs human beta-cells

BACKGROUND: Rodent and human β-cells are differentially susceptible to the “lipotoxic” effects of long-chain saturated fatty acids (LC-SFA) but the factors accounting for this are unclear. Here, we have studied the intracellular disposition of the LC-SFA palmitate in human vs rodent β–cells and pres...

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Detalles Bibliográficos
Autores principales:	Thomas, Patricia, Arden, Catherine, Corcoran, Jenna, Hacker, Christian, Welters, Hannah J., Morgan, Noel G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021209/ https://www.ncbi.nlm.nih.gov/pubmed/35443738 http://dx.doi.org/10.1038/s41387-022-00199-y

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