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Obesity-induced elevated palmitic acid promotes inflammation and glucose metabolism disorders through GPRs/NF-κB/KLF7 pathway

OBJECTIVE: Our previous results have shown that obesity-induced excessive palmitic acid (PA) can promote the expression of KLF7, which plays a vital role in regulation of inflammation, glucose metabolism. But the exact mechanism of PA up-regulating the expression of KLF7 is not clear yet. This study...

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Detalles Bibliográficos
Autores principales: Qiu, Tongtong, Yang, Xin, Wang, Jingzhou, Pan, Chongge, Chu, Xiaolong, Xiong, Jianyu, Xie, Jianxin, Chang, Yongsheng, Wang, Cuizhe, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021212/
https://www.ncbi.nlm.nih.gov/pubmed/35443706
http://dx.doi.org/10.1038/s41387-022-00202-6