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Implication of autophagy in the antifibrogenic effect of Rilpivirine: when more is less

As the main extracellular matrix-producing cells, activated hepatic stellate cells (HSC) are fundamental mediators of liver fibrosis (LF), and understanding their activation/inactivation mechanisms is paramount to the search for novel therapeutics. The antiretroviral drug Rilpivirine (RPV) has demon...

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Detalles Bibliográficos
Autores principales: Lucantoni, Federico, Benedicto, Ana M., Gruevska, Aleksandra, Moragrega, Ángela B., Fuster-Martínez, Isabel, Esplugues, Juan V., Blas-García, Ana, Apostolova, Nadezda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021290/
https://www.ncbi.nlm.nih.gov/pubmed/35443746
http://dx.doi.org/10.1038/s41419-022-04789-7

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