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Exosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts

C-X-C motif chemokine receptor 7 (CXCR7) is a newly discovered atypical chemokine receptor that binds to C-X-C motif chemokine ligand 12 (CXCL12) with higher affinity than CXCR4 and is associated with the metastasis of colorectal cancer (CRC). Cancer-associated fibroblasts (CAFs) have been known to...

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Detalles Bibliográficos
Autores principales: Wang, Dong, Wang, Xiaohui, Song, Yujia, Si, Mahan, Sun, Yuqi, Liu, Xiaohui, Cui, Shuxiang, Qu, Xianjun, Yu, Xinfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021302/
https://www.ncbi.nlm.nih.gov/pubmed/35443745
http://dx.doi.org/10.1038/s41419-022-04825-6