Genetic Deficiency of p53 Leads to Structural, Functional, and Synaptic Deficits in Primary Somatosensory Cortical Neurons of Adult Mice

The tumor suppressor p53 plays a crucial role in embryonic neuron development and neurite growth, and its involvement in neuronal homeostasis has been proposed. To better understand how the lack of the p53 gene function affects neuronal activity, spine development, and plasticity, we examined the el...

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Detalles Bibliográficos
Autores principales: Kuang, Haixia, Liu, Tao, Jiao, Cui, Wang, Jianmei, Wu, Shinan, Wu, Jing, Peng, Sicong, Davidson, Andrew M., Zeng, Shelya X., Lu, Hua, Mostany, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021533/
https://www.ncbi.nlm.nih.gov/pubmed/35465090
http://dx.doi.org/10.3389/fnmol.2022.871974

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