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Prediction and Identification of GPCRs Targeting for Drug Repurposing in Osteosarcoma

BACKGROUND: Osteosarcoma (OS) is a malignant bone tumor common in children and adolescents. The 5-year survival rate is only 67-69% and there is an urgent need to explore novel drugs effective for the OS. G protein-coupled receptors (GPCRs) are the common drug targets and have been found to be assoc...

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Detalles Bibliográficos
Autores principales: Tan, Manli, Gao, Shangzhi, Ru, Xiao, He, Maolin, Zhao, Jinmin, Zheng, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021700/
https://www.ncbi.nlm.nih.gov/pubmed/35463319
http://dx.doi.org/10.3389/fonc.2022.828849