Effects of SGLT2 inhibitor on tumor‐releasing chemokines/cytokines in Hep3B and Huh7 cells

(a) Summary for SGLT2i‐induced alterations in 48 chemokines/cytokines in Hep3B and Huh7 cells. (b) SGLT2i‐induced changes in the medium CXCL1 level (each n = 4). (c) SGLT2i‐induced changes in the medium CXCL8 level (each n = 4). (d) SGLT2i‐induced changes in the medium CXCL10 level (each n = 4), (e)...

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Autores principales: Nakano, Dan, Kawaguchi, Takumi, Tsutsumi, Tsubasa, Hayakawa, Masako, Yoshio, Sachiyo, Koga, Hironori, Torimura, Takuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Publishing Asia Pty Ltd 2022
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021706/
https://www.ncbi.nlm.nih.gov/pubmed/35475201
http://dx.doi.org/10.1002/jgh3.12730
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author Nakano, Dan
Kawaguchi, Takumi
Tsutsumi, Tsubasa
Hayakawa, Masako
Yoshio, Sachiyo
Koga, Hironori
Torimura, Takuji
author_facet Nakano, Dan
Kawaguchi, Takumi
Tsutsumi, Tsubasa
Hayakawa, Masako
Yoshio, Sachiyo
Koga, Hironori
Torimura, Takuji
author_sort Nakano, Dan
collection PubMed
description (a) Summary for SGLT2i‐induced alterations in 48 chemokines/cytokines in Hep3B and Huh7 cells. (b) SGLT2i‐induced changes in the medium CXCL1 level (each n = 4). (c) SGLT2i‐induced changes in the medium CXCL8 level (each n = 4). (d) SGLT2i‐induced changes in the medium CXCL10 level (each n = 4), (e) SGLT2i‐induced changes in the medium M‐CSF level (each n = 4). The SGLT2i‐induced significant changes in chemokines/cytokines are expressed as the percentage of control (the mean value of the control was set as 100%). CXCL, C‐X‐C motif chemokine ligand; G‐CSF, granulocyte colony‐stimulating factor; IL, interleukin; LIF, leukemia inhibitory factor; M‐CSF, macrophage colony‐stimulating factor; MIP‐1α, macrophage inflammatory protein‐1α; SDF‐1α, stromal‐cell‐derived factor‐1α; TNFα, tumor necrosis factor‐α; VEGF, vascular endothelial growth factor.[Image: see text]
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spelling pubmed-90217062022-04-25 Effects of SGLT2 inhibitor on tumor‐releasing chemokines/cytokines in Hep3B and Huh7 cells Nakano, Dan Kawaguchi, Takumi Tsutsumi, Tsubasa Hayakawa, Masako Yoshio, Sachiyo Koga, Hironori Torimura, Takuji JGH Open Brief Reports (a) Summary for SGLT2i‐induced alterations in 48 chemokines/cytokines in Hep3B and Huh7 cells. (b) SGLT2i‐induced changes in the medium CXCL1 level (each n = 4). (c) SGLT2i‐induced changes in the medium CXCL8 level (each n = 4). (d) SGLT2i‐induced changes in the medium CXCL10 level (each n = 4), (e) SGLT2i‐induced changes in the medium M‐CSF level (each n = 4). The SGLT2i‐induced significant changes in chemokines/cytokines are expressed as the percentage of control (the mean value of the control was set as 100%). CXCL, C‐X‐C motif chemokine ligand; G‐CSF, granulocyte colony‐stimulating factor; IL, interleukin; LIF, leukemia inhibitory factor; M‐CSF, macrophage colony‐stimulating factor; MIP‐1α, macrophage inflammatory protein‐1α; SDF‐1α, stromal‐cell‐derived factor‐1α; TNFα, tumor necrosis factor‐α; VEGF, vascular endothelial growth factor.[Image: see text] Wiley Publishing Asia Pty Ltd 2022-03-17 /pmc/articles/PMC9021706/ /pubmed/35475201 http://dx.doi.org/10.1002/jgh3.12730 Text en © 2022 The Authors. JGH Open published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Brief Reports
Nakano, Dan
Kawaguchi, Takumi
Tsutsumi, Tsubasa
Hayakawa, Masako
Yoshio, Sachiyo
Koga, Hironori
Torimura, Takuji
Effects of SGLT2 inhibitor on tumor‐releasing chemokines/cytokines in Hep3B and Huh7 cells
title Effects of SGLT2 inhibitor on tumor‐releasing chemokines/cytokines in Hep3B and Huh7 cells
title_full Effects of SGLT2 inhibitor on tumor‐releasing chemokines/cytokines in Hep3B and Huh7 cells
title_fullStr Effects of SGLT2 inhibitor on tumor‐releasing chemokines/cytokines in Hep3B and Huh7 cells
title_full_unstemmed Effects of SGLT2 inhibitor on tumor‐releasing chemokines/cytokines in Hep3B and Huh7 cells
title_short Effects of SGLT2 inhibitor on tumor‐releasing chemokines/cytokines in Hep3B and Huh7 cells
title_sort effects of sglt2 inhibitor on tumor‐releasing chemokines/cytokines in hep3b and huh7 cells
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021706/
https://www.ncbi.nlm.nih.gov/pubmed/35475201
http://dx.doi.org/10.1002/jgh3.12730
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