Efficacy and Biomarker Exploration of Sintilimab Combined With Chemotherapy in the Treatment of Advanced Penile Squamous Cell Carcinoma—A Report of Two Cases

Penile squamous cell carcinoma is a rare malignant tumor of the male reproductive system. We report two cases of advanced penile squamous cell carcinoma with persistent partial response/complete response after sintilimab combined with chemotherapy and analyze the relevant tumor biomarkers.

Detalles Bibliográficos
Autores principales: Mei, Xinkuan, Zhao, Yanyan, Zhang, Yiruo, Liao, Jinhua, Jiang, Chen, Qian, Hesheng, Du, Yingying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021724/
https://www.ncbi.nlm.nih.gov/pubmed/35463336
http://dx.doi.org/10.3389/fonc.2022.823459
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author Mei, Xinkuan
Zhao, Yanyan
Zhang, Yiruo
Liao, Jinhua
Jiang, Chen
Qian, Hesheng
Du, Yingying
author_facet Mei, Xinkuan
Zhao, Yanyan
Zhang, Yiruo
Liao, Jinhua
Jiang, Chen
Qian, Hesheng
Du, Yingying
author_sort Mei, Xinkuan
collection PubMed
description Penile squamous cell carcinoma is a rare malignant tumor of the male reproductive system. We report two cases of advanced penile squamous cell carcinoma with persistent partial response/complete response after sintilimab combined with chemotherapy and analyze the relevant tumor biomarkers.
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spelling pubmed-90217242022-04-22 Efficacy and Biomarker Exploration of Sintilimab Combined With Chemotherapy in the Treatment of Advanced Penile Squamous Cell Carcinoma—A Report of Two Cases Mei, Xinkuan Zhao, Yanyan Zhang, Yiruo Liao, Jinhua Jiang, Chen Qian, Hesheng Du, Yingying Front Oncol Oncology Penile squamous cell carcinoma is a rare malignant tumor of the male reproductive system. We report two cases of advanced penile squamous cell carcinoma with persistent partial response/complete response after sintilimab combined with chemotherapy and analyze the relevant tumor biomarkers. Frontiers Media S.A. 2022-04-07 /pmc/articles/PMC9021724/ /pubmed/35463336 http://dx.doi.org/10.3389/fonc.2022.823459 Text en Copyright © 2022 Mei, Zhao, Zhang, Liao, Jiang, Qian and Du https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Mei, Xinkuan
Zhao, Yanyan
Zhang, Yiruo
Liao, Jinhua
Jiang, Chen
Qian, Hesheng
Du, Yingying
Efficacy and Biomarker Exploration of Sintilimab Combined With Chemotherapy in the Treatment of Advanced Penile Squamous Cell Carcinoma—A Report of Two Cases
title Efficacy and Biomarker Exploration of Sintilimab Combined With Chemotherapy in the Treatment of Advanced Penile Squamous Cell Carcinoma—A Report of Two Cases
title_full Efficacy and Biomarker Exploration of Sintilimab Combined With Chemotherapy in the Treatment of Advanced Penile Squamous Cell Carcinoma—A Report of Two Cases
title_fullStr Efficacy and Biomarker Exploration of Sintilimab Combined With Chemotherapy in the Treatment of Advanced Penile Squamous Cell Carcinoma—A Report of Two Cases
title_full_unstemmed Efficacy and Biomarker Exploration of Sintilimab Combined With Chemotherapy in the Treatment of Advanced Penile Squamous Cell Carcinoma—A Report of Two Cases
title_short Efficacy and Biomarker Exploration of Sintilimab Combined With Chemotherapy in the Treatment of Advanced Penile Squamous Cell Carcinoma—A Report of Two Cases
title_sort efficacy and biomarker exploration of sintilimab combined with chemotherapy in the treatment of advanced penile squamous cell carcinoma—a report of two cases
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021724/
https://www.ncbi.nlm.nih.gov/pubmed/35463336
http://dx.doi.org/10.3389/fonc.2022.823459
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