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Cyclooxygenase-2 Inhibition as an Add-On Strategy in Drug Resistant Epilepsy—A Canine Translational Study

Drug-resistant epilepsy is a common complaint in dogs and affects up to 30% of dogs with idiopathic epilepsy. Experimental data suggest that targeting cyclooxygenase-2 (COX-2) mediated signaling might limit excessive excitability and prevent ictogenesis. Moreover, the role of COX-2 signaling in the...

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Detalles Bibliográficos
Autores principales: Fischer, Andrea, Hülsmeyer, Velia-Isabel, Munoz Schmieder, Viviana P., Tipold, Andrea, Kornberg, Marion, König, Florian, Gesell, Felix K., Ahrend, Liza K., Volk, Holger A., Potschka, Heidrun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021788/
https://www.ncbi.nlm.nih.gov/pubmed/35464372
http://dx.doi.org/10.3389/fvets.2022.864293