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3D cell culture alters signal transduction and drug response in head and neck squamous cell carcinoma

Epidermal growth factor receptor (EGFR) upregulation is a typical characteristic of head and neck squamous cell carcinoma (HNSCC). However, tyrosine kinase inhibitors have not yet been able to achieve enough therapeutic benefit in clinical trials to justify their use in standard therapy regimens. At...

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Detalles Bibliográficos
Autores principales:	Heid, Jonas, Affolter, Annette, Jakob, Yvonne, Kern, Johann, Rotter, Nicole, Tenschert, Esther, Lammert, Anne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021830/ https://www.ncbi.nlm.nih.gov/pubmed/35464304 http://dx.doi.org/10.3892/ol.2022.13297

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