Vasospasm-induced ST-segment elevation myocardial infarction in a premenopausal woman with endothelial dysfunction

ST-segment elevation myocardial infarction (STEMI) can be caused by coronary artery vasospasm (VSA) due to endothelial dysfunction. However, the clinical role of endothelial function tests in VSA-induced STEMI is not fully understood. We present the case of a 43-year-old woman with atypical chest pa...

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Detalles Bibliográficos
Autores principales: Takase, Bonpei, Kobayashi, Yukie, Sasaki, Natsuko, Hayashi, Katsumi, Hisada, Tetsuya, Sakurada, Masami, Masaki, Nobuyuki, Nagata, Masayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021969/
https://www.ncbi.nlm.nih.gov/pubmed/35464898
http://dx.doi.org/10.1093/omcr/omac040
Descripción
Sumario:ST-segment elevation myocardial infarction (STEMI) can be caused by coronary artery vasospasm (VSA) due to endothelial dysfunction. However, the clinical role of endothelial function tests in VSA-induced STEMI is not fully understood. We present the case of a 43-year-old woman with atypical chest pain and no coronary risk factors. STEMI caused by VSA was diagnosed. Flow-mediated vasodilatation (FMD) and EndPAT tests were performed; the FMD and reactive hyperaemia index were 3.8% and 1.23, respectively. Endothelial dysfunction is the putative cause of STEMI. FMD and EndPAT tests might be useful for predicting adverse outcomes in young premenopausal women with VSA.

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