Vasospasm-induced ST-segment elevation myocardial infarction in a premenopausal woman with endothelial dysfunction

ST-segment elevation myocardial infarction (STEMI) can be caused by coronary artery vasospasm (VSA) due to endothelial dysfunction. However, the clinical role of endothelial function tests in VSA-induced STEMI is not fully understood. We present the case of a 43-year-old woman with atypical chest pa...

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Autores principales: Takase, Bonpei, Kobayashi, Yukie, Sasaki, Natsuko, Hayashi, Katsumi, Hisada, Tetsuya, Sakurada, Masami, Masaki, Nobuyuki, Nagata, Masayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021969/
https://www.ncbi.nlm.nih.gov/pubmed/35464898
http://dx.doi.org/10.1093/omcr/omac040
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author Takase, Bonpei
Kobayashi, Yukie
Sasaki, Natsuko
Hayashi, Katsumi
Hisada, Tetsuya
Sakurada, Masami
Masaki, Nobuyuki
Nagata, Masayoshi
author_facet Takase, Bonpei
Kobayashi, Yukie
Sasaki, Natsuko
Hayashi, Katsumi
Hisada, Tetsuya
Sakurada, Masami
Masaki, Nobuyuki
Nagata, Masayoshi
author_sort Takase, Bonpei
collection PubMed
description ST-segment elevation myocardial infarction (STEMI) can be caused by coronary artery vasospasm (VSA) due to endothelial dysfunction. However, the clinical role of endothelial function tests in VSA-induced STEMI is not fully understood. We present the case of a 43-year-old woman with atypical chest pain and no coronary risk factors. STEMI caused by VSA was diagnosed. Flow-mediated vasodilatation (FMD) and EndPAT tests were performed; the FMD and reactive hyperaemia index were 3.8% and 1.23, respectively. Endothelial dysfunction is the putative cause of STEMI. FMD and EndPAT tests might be useful for predicting adverse outcomes in young premenopausal women with VSA.
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spelling pubmed-90219692022-04-21 Vasospasm-induced ST-segment elevation myocardial infarction in a premenopausal woman with endothelial dysfunction Takase, Bonpei Kobayashi, Yukie Sasaki, Natsuko Hayashi, Katsumi Hisada, Tetsuya Sakurada, Masami Masaki, Nobuyuki Nagata, Masayoshi Oxf Med Case Reports Case Report ST-segment elevation myocardial infarction (STEMI) can be caused by coronary artery vasospasm (VSA) due to endothelial dysfunction. However, the clinical role of endothelial function tests in VSA-induced STEMI is not fully understood. We present the case of a 43-year-old woman with atypical chest pain and no coronary risk factors. STEMI caused by VSA was diagnosed. Flow-mediated vasodilatation (FMD) and EndPAT tests were performed; the FMD and reactive hyperaemia index were 3.8% and 1.23, respectively. Endothelial dysfunction is the putative cause of STEMI. FMD and EndPAT tests might be useful for predicting adverse outcomes in young premenopausal women with VSA. Oxford University Press 2022-04-19 /pmc/articles/PMC9021969/ /pubmed/35464898 http://dx.doi.org/10.1093/omcr/omac040 Text en © The Author(s) 2022. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Takase, Bonpei
Kobayashi, Yukie
Sasaki, Natsuko
Hayashi, Katsumi
Hisada, Tetsuya
Sakurada, Masami
Masaki, Nobuyuki
Nagata, Masayoshi
Vasospasm-induced ST-segment elevation myocardial infarction in a premenopausal woman with endothelial dysfunction
title Vasospasm-induced ST-segment elevation myocardial infarction in a premenopausal woman with endothelial dysfunction
title_full Vasospasm-induced ST-segment elevation myocardial infarction in a premenopausal woman with endothelial dysfunction
title_fullStr Vasospasm-induced ST-segment elevation myocardial infarction in a premenopausal woman with endothelial dysfunction
title_full_unstemmed Vasospasm-induced ST-segment elevation myocardial infarction in a premenopausal woman with endothelial dysfunction
title_short Vasospasm-induced ST-segment elevation myocardial infarction in a premenopausal woman with endothelial dysfunction
title_sort vasospasm-induced st-segment elevation myocardial infarction in a premenopausal woman with endothelial dysfunction
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021969/
https://www.ncbi.nlm.nih.gov/pubmed/35464898
http://dx.doi.org/10.1093/omcr/omac040
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