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Severe acidosis due to 5-oxoprolinase inhibition by flucloxacillin in a patient with shoulder prosthesis joint infection

We report a case of a 64-year-old female patient with severe metabolic acidosis. Inhibition of 5-oxoprolinase by flucloxacillin was found to be the cause of the metabolic derailment.

Detalles Bibliográficos
Autores principales: Lenz, Julia Elisabeth, Alt, Volker, Dienemann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Copernicus GmbH 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022110/
https://www.ncbi.nlm.nih.gov/pubmed/35464148
http://dx.doi.org/10.5194/jbji-7-71-2022
Descripción
Sumario:We report a case of a 64-year-old female patient with severe metabolic acidosis. Inhibition of 5-oxoprolinase by flucloxacillin was found to be the cause of the metabolic derailment.