Severe acidosis due to 5-oxoprolinase inhibition by flucloxacillin in a patient with shoulder prosthesis joint infection

We report a case of a 64-year-old female patient with severe metabolic acidosis. Inhibition of 5-oxoprolinase by flucloxacillin was found to be the cause of the metabolic derailment.

Detalles Bibliográficos
Autores principales: Lenz, Julia Elisabeth, Alt, Volker, Dienemann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Copernicus GmbH 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022110/
https://www.ncbi.nlm.nih.gov/pubmed/35464148
http://dx.doi.org/10.5194/jbji-7-71-2022
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author Lenz, Julia Elisabeth
Alt, Volker
Dienemann, Thomas
author_facet Lenz, Julia Elisabeth
Alt, Volker
Dienemann, Thomas
author_sort Lenz, Julia Elisabeth
collection PubMed
description We report a case of a 64-year-old female patient with severe metabolic acidosis. Inhibition of 5-oxoprolinase by flucloxacillin was found to be the cause of the metabolic derailment.
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spelling pubmed-90221102022-04-22 Severe acidosis due to 5-oxoprolinase inhibition by flucloxacillin in a patient with shoulder prosthesis joint infection Lenz, Julia Elisabeth Alt, Volker Dienemann, Thomas J Bone Jt Infect Case Report We report a case of a 64-year-old female patient with severe metabolic acidosis. Inhibition of 5-oxoprolinase by flucloxacillin was found to be the cause of the metabolic derailment. Copernicus GmbH 2022-04-04 /pmc/articles/PMC9022110/ /pubmed/35464148 http://dx.doi.org/10.5194/jbji-7-71-2022 Text en Copyright: © 2022 Julia Elisabeth Lenz et al. https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this licence, visit https://creativecommons.org/licenses/by/4.0/
spellingShingle Case Report
Lenz, Julia Elisabeth
Alt, Volker
Dienemann, Thomas
Severe acidosis due to 5-oxoprolinase inhibition by flucloxacillin in a patient with shoulder prosthesis joint infection
title Severe acidosis due to 5-oxoprolinase inhibition by flucloxacillin in a patient with shoulder prosthesis joint infection
title_full Severe acidosis due to 5-oxoprolinase inhibition by flucloxacillin in a patient with shoulder prosthesis joint infection
title_fullStr Severe acidosis due to 5-oxoprolinase inhibition by flucloxacillin in a patient with shoulder prosthesis joint infection
title_full_unstemmed Severe acidosis due to 5-oxoprolinase inhibition by flucloxacillin in a patient with shoulder prosthesis joint infection
title_short Severe acidosis due to 5-oxoprolinase inhibition by flucloxacillin in a patient with shoulder prosthesis joint infection
title_sort severe acidosis due to 5-oxoprolinase inhibition by flucloxacillin in a patient with shoulder prosthesis joint infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022110/
https://www.ncbi.nlm.nih.gov/pubmed/35464148
http://dx.doi.org/10.5194/jbji-7-71-2022
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AT dienemannthomas severeacidosisdueto5oxoprolinaseinhibitionbyflucloxacillininapatientwithshoulderprosthesisjointinfection

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