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Rotavirus-Induced Expansion of Antigen-Specific CD8 T Cells Does Not Require Signaling via TLR3, MyD88 or the Type I Interferon Receptor

Rotavirus (RV) infection induces strong adaptive immunity. While protection from reinfection requires humoral immunity, initial clearance of infection depends on cytotoxic CD8 T cells. Type I classical dendritic cells (cDC1) excel at CD8 T cell induction through cross-presentation and are essential...

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Detalles Bibliográficos
Autores principales: Muleta, Konjit Getachew, Ulmert, Isabel, Hamza, Kedir Hussen, van Dijl, Sharné, Nakawesi, Joy, Lahl, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022177/
https://www.ncbi.nlm.nih.gov/pubmed/35464475
http://dx.doi.org/10.3389/fimmu.2022.814491