The SARS-CoV-2 receptor ACE2 is expressed in mouse pericytes but not endothelial cells: Implications for COVID-19 vascular research

Humanized mouse models and mouse-adapted SARS-CoV-2 virus are increasingly used to study COVID-19 pathogenesis, so it is important to learn where the SARS-CoV-2 receptor ACE2 is expressed. Here we mapped ACE2 expression during mouse postnatal development and in adulthood. Pericytes in the CNS, heart...

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Detalles Bibliográficos
Autores principales: Muhl, Lars, He, Liqun, Sun, Ying, Andaloussi Mäe, Maarja, Pietilä, Riikka, Liu, Jianping, Genové, Guillem, Zhang, Lei, Xie, Yuan, Leptidis, Stefanos, Mocci, Giuseppe, Stritt, Simon, Osman, Ahmed, Anisimov, Andrey, Hemanthakumar, Karthik Amudhala, Räsänen, Markus, Hansson, Emil M., Björkegren, Johan, Vanlandewijck, Michael, Blomgren, Klas, Mäkinen, Taija, Peng, Xiao-Rong, Hu, Yizhou, Ernfors, Patrik, Arnold, Thomas D., Alitalo, Kari, Lendahl, Urban, Betsholtz, Christer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022216/
https://www.ncbi.nlm.nih.gov/pubmed/35452595
http://dx.doi.org/10.1016/j.stemcr.2022.03.016

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